Perbedaan Derajat Keparahan Akne Vulgaris berdasarkan Pemakaian Alphadan Beta Hydroxy Acid
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Abstract
Background : Indonesia has a tropical climate that gets very strong sun exposure. With extreme weather conditions, various skin problems can be seen, one of which is acne vulgaris. Topical therapy is the preferred choice for the treatment of mild to moderate acne and is also helpful for the treatment of severe acne, such as alpha hydroxy acids and beta hydroxy acids (AHAs and BHAs).
Objective : To determine the differences in the severity of acne vulgaris based on the use of alpha hydroxy acid and beta hydroxy acid (AHA and BHA) in 6th semester students of the Hang Tuah University Faculty of Medicine.
Methods: An analytic observational method in a cross sectional study with a simple random sampling method. The study was conducted from April to December using 58 samples by distributing questionnaires through the google form link.
Results : The Mann-Whitney U statistical test between users and non-users of alpha hydroxy acid and beta hydroxy acid (AHA and BHA) showed a significance 0,068. So there was no difference in the two groups.
Conclusion : The most classification of acne vulgaris severity is mild in female students who use and do not use alpha hydroxy acid and beta hydroxy acid (AHA and BHA).
Keywords : AHA and BHA, Acne Vulgaris, Facial Skin.
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References
Araviiskaia, E. and Dréno, B., 2016. The role of topical dermocosmetics in acne vulgaris. Journal of the European Academy of Dermatology and Venereology.
Arif, T., 2015. Salicylic acid as a peeling agent: A comprehensive review. Clinical, Cosmetic and Investigational Dermatology.
Baldwin, H. and Tan, J., 2021. Effects of Diet on Acne and Its Response to Treatment. American Journal of Clinical Dermatology.
Bourelly, P.F. and Lotsikas-Baggilli, A.J., 2005. Chemexfoliation and Superficial Skin Resurfacing. In: C.M. Burgess, ed. Cosmetic Dermatology. p.62.
Carol, K.C., Stephen, M.A., Mietzner, T. and Miller, S., 2016. Infection Caused by Anaerobic Bacteria. In: Jawetz, Melnick & Adelberg’s Medical Microbiology, 27th ed. p.295.
Cong, T.X., Hao, D., Wen, X., Li, X.H., He, G. and Jiang, X., 2019. From pathogenesis of acne vulgaris to anti-acne agents. Archives of Dermatological Research.
Draelos, Z., Lewis, J., McHugh, L., Pellegrino, A. and Popescu, L., 2016. Novel retinoid ester in combination with salicylic acid for the treatment of acne. Journal of Cosmetic Dermatology.
Fiume, M.M. and Heldreth, B., 2017. Alpha Hydroxy Acids. International Journal of Toxicology.
Fox, L., Csongradi, C., Aucamp, M., Du Plessis, J. and Gerber, M., 2016. Treatment modalities for acne. Molecules.
Goh, C., Chen, C., Agak, G., Zaenglein, A.L., Graber, E.M., Thiboutot, D.M. and Kim, J., 2018. Acne vulgaris. In: Fitzpatrick Dermatology, 9th ed. pp.1391– 1397.
Graf, J., 2005. Anti-Aging Skin Care Ingredient Technologies. In: C.M. Burgess, ed. Cosmetic Dermatology. p.24.
Habif, T.P., 2016. Clinical Dermatology. 6th ed.
Heng, A.H.S., Say, Y.H., Sio, Y.Y., Ng, Y.T. and Chew, F.T., 2021. Epidemiological Risk Factors Associated with Acne Vulgaris Presentation, Severity, and Scarring in a Singapore Chinese Population: A Cross- Sectional Study. Dermatology.
Jones, R.M., 2019. Acne, Rosacea, and Hidradenitis Suppurativa. In: R.M. Jones, ed. ABC of Dermatology, 7th ed.
Kurokawa, I. and Nakase, K., 2020. Recent advances in understanding and managing acne. F1000Research.
Liu, H., Yu, H., Xia, J., Liu, L., Liu, G., Sang, H. and Peinemann, F., 2020. Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. Journal of Evidence-Based Medicine.
Lu, J., Cong, T., Wen, X., Li, X., Du, D., He, G. and Jiang, X., 2019. Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes. Experimental Dermatology.
Lynn, D., Umari, T., Dellavalle, R. and Dunnick, C., 2016. The epidemiology of acne vulgaris in late adolescence. Adolescent Health, Medicine and Therapeutics.
Marks, J.G. and Miller, J.J., 2019. Pustules. In: Lookingbill and Marks’ Principles of Dermatolofy, 6th ed. p.169.
Mlacker, S., Shafa, G., Aldahan, A.S. and Keyvan, N., 2018. Acne. In: J.G. Albertini, J.S. Bordeaux, L.M. Dzubow, N. Lawrence and S.J. Miller, eds. Dermatologic Surgery.
Notoatmodjo, S., 2018. Metodologi Penelitian Kesehatan.
Oon, H.H., Wong, S.N., Wee, D.C.A.W., Cheong, W.K., Goh, C.L. and Tan, H.H., 2019. Acne management guidelines by the Dermatological society of Singapore. Journal of Clinical and Aesthetic Dermatology.
Patrishia, L., 2019. Pentingnya Pemilihan Eksfoliator dalam Mengangkat Sel Kulit Mati pada WajahNo Title.
Ramli, R., Malik, A.S., Hani, A.F.M. and Jamil, A., 2012. Acne analysis, grading and computational assessment methods: An overview. Skin Research and T echnology.
Saxena, V. and Yadav, K., 2020. Glycolic Acid, Lactic Acid, Mandelic Acid, Salicylic Acid, Citric Acid, Gluconolactone: Skin Exfoliators in Combination Therapy of Acne Vulgaris. International Journal of Research in Engineering, Science and Management.
Surahman, Rachmat, M., Supardi, S. and Toha, M., 2016. Metodologi Penelitian. Tang, S.C. and Yang, J.H., 2018. Dual effects of alpha-hydroxy acids on the skin.
Molecules.
Zaenglein, A.L. and Thiboutot, D.M., 2012. Acne Vulgaris. In: J.L. Bolognia, J.L.
Jorizzo and J. V. Schaffer, eds. Dermatology, 3rd ed. pp.545–547.