Pengaruh Ekstrak Jahe Merah  (Zingiber Officinale.)  Terhadap Pertumbuhan  Bakteri Shigella Dysentriae

NI KADEK SINTA DWI CHRISMASYANTI; KADEK DENIK SUASTINI; NI LUH SURAS AMOURA CAWIS; NI WAYAN SUCINDRA DEWI

doi:10.30649/htmj.v18i2.119

Authors

NI KADEK SINTA DWI CHRISMASYANTI Fakultas Kedokteran Universitas Udayana
KADEK DENIK SUASTINI Fakultas Kedokteran Universitas Udayana
NI LUH SURAS AMOURA CAWIS Fakultas Kedokteran Universitas Udayana
NI WAYAN SUCINDRA DEWI Departemen Farmakologi dan Terapi Fakultas Kedokteran Universitas Udayana

DOI:

https://doi.org/10.30649/htmj.v18i2.119

Keywords:

Red Ginger, Dysentery, Flavonoids

Abstract

Abstract
Diarrheal disease in Indonesia is still a high health problem for its morbidity and mortality rates. Diarrhea is still a cause of death in children under 5 years, amounting to 25.2%. Diarrhea morbidity in Indonesia during 2015 reached 6,897,463 and diarrhea that had been handled reached 2,544,084 or as much as 36.9%. The most important and most common cause of diarrhea in developing countries is Shigella, especially Shigella dysentriae and Shigella boydi which causes diarrhea with dysentery. One natural ingredient that has the potential to treat Shigella Dysentriae bacteria is ginger (Zingiber officinale). The ginger plant itself is very abundant in Indonesia. The antibacterial effect against Shigella dysenteriae is due to the active ingredient in ginger, namely gingerol, which inhibits the antibacterial activity of phenolics, flavonoids with an inhibitory mechanism by denaturing bacterial cell wall proteins.